| Wigan Borough v Nelson 03/09/1921 | View match | |
| Lincoln City FC v Nelson 10/09/1921 | View match | |
| Darlington FC v Nelson 24/09/1921 | View match | |
| Accrington Stanley (1891) v Nelson 08/10/1921 | View match | |
| Chesterfield FC v Nelson 22/10/1921 | View match | |
| Crewe Alexandra FC v Nelson 05/11/1921 | View match | |
| Wrexham FC v Nelson 26/11/1921 | View match | |
| Barrow v Nelson 24/12/1921 | View match | |
| Stalybridge Celtic v Nelson 27/12/1921 | View match | |
| Ashington v Nelson 31/12/1921 | View match | |
| Hartlepool United v Nelson 28/01/1922 | View match | |
| Southport v Nelson 11/02/1922 | View match |