| Northampton Town FC v Scunthorpe United FC 04/09/2021 | £8.50 | |
| Forest Green Rovers v Northampton Town FC 11/09/2021 | View match | |
| Newport County AFC v Northampton Town FC 14/09/2021 | £7.50 | |
| Northampton Town FC v Swindon Town FC 18/09/2021 | £8.50 | |
| Salford City v Northampton Town FC 25/09/2021 | View match | |
| Northampton Town FC v Sutton United 02/10/2021 | View match | |
| Northampton Town FC v Walsall FC 05/10/2021 | View match | |
| Hartlepool United v Northampton Town FC 09/10/2021 | View match | |
| Northampton Town FC v Mansfield Town FC 16/10/2021 | View match | |
| Northampton Town FC v Stevenage Borough FC 19/10/2021 | View match | |
| Tranmere Rovers FC v Northampton Town FC 23/10/2021 | £7.50 | |
| Northampton Town FC v Carlisle United FC 30/10/2021 | View match |