| Stoke City FC v Port Vale FC 07/09/1925 | View match | |
| Hull City FC v Port Vale FC 12/09/1925 | View match | |
| Port Vale FC v Barnsley FC 14/09/1925 | View match | |
| Port Vale FC v Darlington FC 19/09/1925 | View match | |
| Blackpool FC v Port Vale FC 26/09/1925 | View match | |
| Port Vale FC v Southampton FC 03/10/1925 | View match | |
| Nottingham Forest FC v Port Vale FC 10/10/1925 | View match | |
| Oldham Athletic FC v Port Vale FC 17/10/1925 | View match | |
| Port Vale FC v Stockport County FC 24/10/1925 | View match | |
| Swansea Town v Port Vale FC 31/10/1925 | View match | |
| Port Vale FC v The Wednesday 07/11/1925 | View match | |
| Preston North End FC v Port Vale FC 14/11/1925 | View match |