| Port Vale FC v Wimbledon 31/01/1981 | View match | |
| Aldershot F.C v Port Vale FC 07/02/1981 | View match | |
| Port Vale FC v Wigan Athletic FC 14/02/1981 | View match | |
| Port Vale FC v Bury FC 21/02/1981 | View match | |
| Scunthorpe United FC v Port Vale FC 24/02/1981 | View match | |
| Port Vale FC v Scunthorpe United FC 03/03/1981 | View match | |
| Port Vale FC v York City FC 07/03/1981 | View match | |
| Port Vale FC v Hereford United 16/03/1981 | View match | |
| Tranmere Rovers FC v Port Vale FC 24/03/1981 | View match | |
| AFC Bournemouth v Port Vale FC 28/03/1981 | View match | |
| Port Vale FC v Peterborough United FC 04/04/1981 | View match | |
| Rochdale FC v Port Vale FC 12/04/1981 | View match |