| Carlisle United FC v Port Vale FC 17/04/2021 | View match | |
| Barrow AFC v Port Vale FC 20/04/2021 | View match | |
| Port Vale FC v Bradford City FC 24/04/2021 | View match | |
| Grimsby Town FC v Port Vale FC 01/05/2021 | View match | |
| Port Vale FC v Mansfield Town FC 08/05/2021 | View match | |
| Northampton Town FC v Port Vale FC 07/08/2021 | £8.50 | |
| Port Vale FC v Sunderland FC 10/08/2021 | View match | |
| Port Vale FC v Tranmere Rovers FC 14/08/2021 | View match | |
| Port Vale FC v Carlisle United FC 17/08/2021 | View match | |
| Stevenage Borough FC v Port Vale FC 21/08/2021 | View match | |
| Forest Green Rovers v Port Vale FC 28/08/2021 | View match | |
| Bolton Wanderers FC v Port Vale FC 31/08/2021 | View match |