| Millwall FC v Portsmouth FC 19/10/2010 | £5.50 | |
| Hull City FC v Portsmouth FC 23/10/2010 | £5.50 | |
| Portsmouth FC v Nottingham Forest FC 30/10/2010 | £5.50 | |
| Derby County FC v Portsmouth FC 06/11/2010 | £5.50 | |
| Portsmouth FC v Queens Park Rangers FC 09/11/2010 | £5.50 | |
| Portsmouth FC v Doncaster Rovers FC 13/11/2010 | £5.50 | |
| Barnsley FC v Portsmouth FC 20/11/2010 | £5.50 | |
| Swansea City FC v Portsmouth FC 26/11/2010 | £5.50 | |
| Norwich City FC v Portsmouth FC 11/12/2010 | £5.50 | |
| Portsmouth FC v Scunthorpe United FC 18/12/2010 | £7.50 | |
| Portsmouth FC v Millwall FC 26/12/2010 | £5.50 | |
| Leeds United FC v Portsmouth FC 28/12/2010 | £5.50 |