| Southampton FC v Sheffield Wednesday FC 27/01/2001 | £2.00 | |
| Southampton FC v Leicester City FC 31/01/2001 | £4.00 | |
| Southampton FC v Bradford City FC 10/02/2001 | £5.50 | |
| Southampton FC v Bradford City FC 10/02/2001 | £2.50 | |
| Southampton FC v Tranmere Rovers FC 17/02/2001 | £5.50 | |
| Southampton FC v Tranmere Rovers FC 17/02/2001 | £4.00 | |
| Tranmere Rovers FC v Southampton FC 20/02/2001 | View match | |
| Middlesbrough FC v Southampton FC 24/02/2001 | View match | |
| Manchester City FC v Southampton FC 03/03/2001 | £4.00 | |
| Southampton FC v Everton FC 17/03/2001 | £5.00 | |
| Southampton FC v Ipswich Town FC 02/04/2001 | £6.50 | |
| Southampton FC v Ipswich Town FC 02/04/2001 | £4.00 |