| Southport v Northampton Town FC 04/03/1961 | View match | |
| Aldershot F.C v Southport 11/03/1961 | View match | |
| Southport v Oldham Athletic FC 18/03/1961 | View match | |
| York City FC v Southport 20/03/1961 | View match | |
| Workington v Southport 25/03/1961 | View match | |
| Southport v Gillingham FC 31/03/1961 | View match | |
| Southport v Chester City FC 01/04/1961 | View match | |
| Gillingham FC v Southport 03/04/1961 | View match | |
| Crewe Alexandra FC v Southport 08/04/1961 | View match | |
| Southport v York City FC 15/04/1961 | View match | |
| Accrington Stanley (1891) v Southport 22/04/1961 | View match | |
| Southport v Peterborough United FC 25/04/1961 | View match |