| Southport v York City FC 11/09/1951 | View match | |
| Southport v Stockport County FC 15/09/1951 | View match | |
| Southport v Tranmere Rovers FC 22/09/1951 | View match | |
| Scunthorpe United FC v Southport 29/09/1951 | View match | |
| Barrow v Southport 06/10/1951 | View match | |
| Southport v Grimsby Town FC 13/10/1951 | View match | |
| Wrexham FC v Southport 20/10/1951 | View match | |
| Southport v Chesterfield FC 27/10/1951 | View match | |
| Bradford Park Avenue v Southport 03/11/1951 | View match | |
| Southport v Halifax Town A.F.C 10/11/1951 | View match | |
| Mansfield Town FC v Southport 17/11/1951 | View match | |
| Bangor City v Southport 24/11/1951 | View match |