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| Southampton FC v West Ham United FC 11/09/2021 | £7.50 | |
| West Ham United FC v Manchester United FC 19/09/2021 | £7.50 | |
| Manchester United FC v West Ham United FC 22/09/2021 | £5.99 | |
| Leeds United FC v West Ham United FC 25/09/2021 | £7.50 | |
| West Ham United FC v Rapid Wien 30/09/2021 | View match | |
| West Ham United FC v Brentford FC 03/10/2021 | View match | |
| Everton FC v West Ham United FC 17/10/2021 | £7.50 | |
| West Ham United FC v Racing Genk 21/10/2021 | £7.50 | |
| West Ham United FC v Tottenham Hotspur FC 24/10/2021 | View match | |
| West Ham United FC v Manchester City FC 27/10/2021 | £7.50 | |
| Aston Villa FC v West Ham United FC 31/10/2021 | View match |