| Bristol Rovers FC v Wrexham FC 06/12/1980 | View match | |
| Wrexham FC v Cambridge United FC 13/12/1980 | View match | |
| Preston North End FC v Wrexham FC 20/12/1980 | View match | |
| Wrexham FC v Bolton Wanderers FC 26/12/1980 | View match | |
| Shrewsbury Town FC v Wrexham FC 27/12/1980 | View match | |
| West Ham United FC v Wrexham FC 03/01/1981 | View match | |
| Wrexham FC v West Ham United FC 06/01/1981 | View match | |
| Wrexham FC v Newcastle United FC 10/01/1981 | View match | |
| Wrexham FC v West Ham United FC 19/01/1981 | View match | |
| Wrexham FC v Wimbledon 24/01/1981 | View match | |
| Wrexham FC v Grimsby Town FC 31/01/1981 | View match | |
| Orient v Wrexham FC 07/02/1981 | View match |