| Bradford City FC v Wrexham FC 14/09/1949 | View match | |
| Tranmere Rovers FC v Wrexham FC 17/09/1949 | View match | |
| Wrexham FC v York City FC 24/09/1949 | View match | |
| Oldham Athletic FC v Wrexham FC 01/10/1949 | View match | |
| Chester City FC v Wrexham FC 08/10/1949 | View match | |
| Wrexham FC v Southport 15/10/1949 | View match | |
| Stockport County FC v Wrexham FC 22/10/1949 | View match | |
| Wrexham FC v Doncaster Rovers FC 29/10/1949 | View match | |
| Gateshead v Wrexham FC 05/11/1949 | View match | |
| Wrexham FC v Hartlepool United 12/11/1949 | View match | |
| Darlington FC v Wrexham FC 19/11/1949 | View match | |
| Wrexham FC v Grantham Town 26/11/1949 | View match |