| Southampton FC v Chelsea FC 04/11/2000 | £4.50 | |
| Sunderland FC v Southampton FC 11/11/2000 | View match | |
| Southampton FC v Aston Villa FC 18/11/2000 | £1.50 | |
| Southampton FC v Aston Villa FC 18/11/2000 | £2.50 | |
| Southampton FC v West Ham United FC 25/11/2000 | £2.50 | |
| Southampton FC v West Ham United FC 25/11/2000 | £2.50 | |
| Arsenal FC v Southampton FC 02/12/2000 | £1.50 | |
| Arsenal FC v Southampton FC 02/12/2000 | £3.00 | |
| Southampton FC v Leeds United FC 09/12/2000 | £5.00 | |
| Ipswich Town FC v Southampton FC 16/12/2000 | £5.00 | |
| Coventry City FC v Southampton FC 22/12/2000 | View match | |
| Southampton FC v Tottenham Hotspur FC 27/12/2000 | £4.50 |