| Southampton FC v Luton Town FC 02/01/2010 | £4.90 | |
| Millwall FC v Southampton FC 16/01/2010 | View match | |
| Southampton FC v Ipswich Town FC 23/01/2010 | £7.00 | |
| Brentford FC v Southampton FC 26/01/2010 | View match | |
| Southampton FC v Stockport County FC 30/01/2010 | View match | |
| Exeter City FC v Southampton FC 06/02/2010 | View match | |
| Southampton FC v Portsmouth FC 13/02/2010 | View match | |
| Norwich City FC v Southampton FC 20/02/2010 | View match | |
| Wycombe Wanderers FC v Southampton FC 23/02/2010 | View match | |
| Southampton FC v Walsall FC 27/02/2010 | £4.90 | |
| Southampton FC v Huddersfield Town FC 02/03/2010 | £4.90 | |
| Tranmere Rovers FC v Southampton FC 06/03/2010 | View match |