| Southampton FC v Bradford Park Avenue 03/12/1949 | £20.99 | |
| Leicester City FC v Southampton FC 10/12/1949 | View match | |
| Grimsby Town FC v Southampton FC 17/12/1949 | View match | |
| Southampton FC v Queens Park Rangers FC 24/12/1949 | View match | |
| Luton Town FC v Southampton FC 26/12/1949 | View match | |
| Southampton FC v Luton Town FC 27/12/1949 | View match | |
| Preston North End FC v Southampton FC 31/12/1949 | View match | |
| Northampton Town FC v Southampton FC 07/01/1950 | View match | |
| Southampton FC v Northampton Town FC 11/01/1950 | £25.00 | |
| Southampton FC v Swansea Town 14/01/1950 | View match | |
| Leeds United FC v Southampton FC 21/01/1950 | View match | |
| Southampton FC v Torquay United FC 28/01/1950 | View match |