| Southampton FC v Manchester United FC 22/08/2021 | £7.50 | |
| Arsenal FC v Chelsea FC 22/08/2021 | £7.50 | |
| Wolverhampton Wanderers FC v Tottenham Hotspur FC 22/08/2021 | £5.00 | |
| Swansea City FC v Plymouth Argyle FC 24/08/2021 | £8.50 | |
| Barrow AFC v Aston Villa FC 24/08/2021 | £11.99 | |
| Blackpool FC v Sunderland FC 24/08/2021 | £7.50 | |
| Cardiff City FC v Brighton & Hove Albion FC 24/08/2021 | £8.00 | |
| Cardiff City FC v Brighton & Hove Albion FC 24/08/2021 | £7.50 | |
| Leeds United FC v Crewe Alexandra FC 24/08/2021 | £7.50 | |
| Morecambe FC v Preston North End FC 24/08/2021 | £9.50 | |
| Newport County AFC v Southampton FC 25/08/2021 | £8.50 | |
| West Bromwich Albion FC v Arsenal FC 25/08/2021 | £7.50 |