| Luton Town FC v Sheffield United FC 28/08/2021 | £9.50 | |
| Middlesbrough FC v Blackburn Rovers FC 28/08/2021 | £7.50 | |
| Peterborough United FC v West Bromwich Albion FC 28/08/2021 | £7.50 | |
| Ipswich Town FC v AFC Wimbledon FC 28/08/2021 | £7.50 | |
| Morecambe FC v Sheffield Wednesday FC 28/08/2021 | £9.50 | |
| Plymouth Argyle FC v Fleetwood Town FC 28/08/2021 | £7.50 | |
| Manchester City FC v Arsenal FC 28/08/2021 | £8.50 | |
| Brighton & Hove Albion FC v Everton FC 28/08/2021 | £7.50 | |
| Brighton & Hove Albion FC v Everton FC 28/08/2021 | £5.00 | |
| Wolverhampton Wanderers FC v Manchester United FC 29/08/2021 | £7.50 | |
| Sheffield Wednesday FC v Newcastle United (U21`s) 31/08/2021 | £7.50 | |
| Rochdale FC v Liverpool (U21`s) 31/08/2021 | £7.50 |