| Luton Town FC v AFC Bournemouth 15/01/2022 | £7.50 | |
| Millwall FC v Nottingham Forest FC 15/01/2022 | £7.50 | |
| Preston North End FC v Birmingham City FC 15/01/2022 | £7.50 | |
| Liverpool FC v Brentford FC 16/01/2022 | £7.50 | |
| Fulham FC v Birmingham City FC 18/01/2022 | £7.50 | |
| AFC Wimbledon FC v Portsmouth FC 18/01/2022 | £7.50 | |
| Leicester City FC v Tottenham Hotspur FC 19/01/2022 | £7.50 | |
| Arsenal FC v Liverpool FC 20/01/2022 | £7.50 | |
| Barrow AFC v Mansfield Town FC 22/01/2022 | £9.50 | |
| Rochdale FC v Bradford City FC 22/01/2022 | £7.50 | |
| Swindon Town FC v Bristol Rovers FC 22/01/2022 | £5.99 | |
| Burton Albion FC v AFC Wimbledon FC 22/01/2022 | £7.50 |