| Nottingham Forest FC v West Bromwich Albion FC 18/04/2022 | £7.50 | |
| AFC Wimbledon FC v Wycombe Wanderers FC 18/04/2022 | £7.50 | |
| Cambridge United FC v Charlton Athletic FC 19/04/2022 | £7.50 | |
| Sheffield Wednesday FC v Crewe Alexandra FC 19/04/2022 | £7.50 | |
| Liverpool FC v Manchester United FC 19/04/2022 | £7.50 | |
| Manchester City FC v Brighton & Hove Albion FC 20/04/2022 | £7.50 | |
| Manchester City FC v Brighton & Hove Albion FC 20/04/2022 | £8.50 | |
| Chelsea FC v Arsenal FC 20/04/2022 | £8.50 | |
| Huddersfield Town FC v Barnsley FC 22/04/2022 | £7.50 | |
| Luton Town FC v Blackpool FC 23/04/2022 | £7.50 | |
| Swansea City FC v Middlesbrough FC 23/04/2022 | £8.50 | |
| AFC Bournemouth v Fulham FC 23/04/2022 | £7.50 |