| Burnley FC v Southampton FC 24/09/2011 | £5.50 | |
| Cardiff City FC v Southampton FC 28/09/2011 | £5.50 | |
| Southampton FC v Watford FC 01/10/2011 | £7.00 | |
| Southampton FC v West Ham United FC 18/10/2011 | £7.50 | |
| Crystal Palace FC v Southampton FC 25/10/2011 | £5.50 | |
| Southampton FC v Middlesbrough FC 29/10/2011 | £7.50 | |
| Southampton FC v Peterborough United FC 01/11/2011 | £7.00 | |
| Coventry City FC v Southampton FC 05/11/2011 | £7.00 | |
| Southampton FC v Brighton & Hove Albion FC 19/11/2011 | £7.00 | |
| Bristol City FC v Southampton FC 26/11/2011 | £5.50 | |
| Doncaster Rovers FC v Southampton FC 03/12/2011 | £7.50 | |
| Southampton FC v Blackpool FC 10/12/2011 | £7.00 |