| Southport v Stevenage Borough FC 20/08/2005 | View match | |
| Kidderminister Harriers v Southport 27/08/2005 | View match | |
| Southport v Burton Albion FC 29/08/2005 | View match | |
| Gravesend & Northfleet v Southport 03/09/2005 | View match | |
| Woking FC v Southport 10/09/2005 | View match | |
| Southport v Exeter City FC 17/09/2005 | View match | |
| Southport v Tamworth 20/09/2005 | View match | |
| Canvey Island v Southport 24/09/2005 | View match | |
| Scarborough FC v Southport 27/09/2005 | View match | |
| Southport v Cambridge United FC 01/10/2005 | View match | |
| Southport v Forest Green Rovers 07/10/2005 | View match | |
| Altrincham v Southport 15/10/2005 | View match |