| York City FC v Southport 23/11/2010 | View match | |
| Fleetwood Town FC v Southport 28/12/2010 | View match | |
| Barrow AFC v Southport 01/01/2011 | View match | |
| Southport v Gateshead 03/01/2011 | View match | |
| Southport v Newport County AFC 08/01/2011 | View match | |
| Southport v Wrexham FC 18/01/2011 | View match | |
| AFC Wimbledon FC v Southport 22/01/2011 | View match | |
| Southport v York City FC 29/01/2011 | View match | |
| Southport v Grimsby Town FC 01/02/2011 | View match | |
| Southport v Forest Green Rovers 12/02/2011 | View match | |
| Hayes & Yeading United v Southport 19/02/2011 | View match | |
| Crawley Town FC v Southport 22/02/2011 | View match |