| Southampton FC v Watford FC 27/01/2018 | View match | |
| Southampton FC v Brighton & Hove Albion FC 31/01/2018 | £6.50 | |
| West Bromwich Albion FC v Southampton FC 03/02/2018 | £6.50 | |
| Southampton FC v Liverpool FC 11/02/2018 | View match | |
| West Bromwich Albion FC v Southampton FC 17/02/2018 | View match | |
| Burnley FC v Southampton FC 24/02/2018 | View match | |
| Southampton FC v Stoke City FC 03/03/2018 | View match | |
| Newcastle United FC v Southampton FC 10/03/2018 | View match | |
| Wigan Athletic FC v Southampton FC 18/03/2018 | View match | |
| West Ham United FC v Southampton FC 31/03/2018 | View match | |
| Arsenal FC v Southampton FC 08/04/2018 | View match | |
| Southampton FC v Chelsea FC 14/04/2018 | View match |