| Marlow FC v Clarence 30/10/1880 | View match | |
| Sheffield F.C v Blackburn Olympic 30/10/1880 | View match | |
| Notts County FC v Derbyshire FC 04/11/1880 | View match | |
| Brentwood Town v Old Etonians 06/11/1880 | View match | |
| Spilsby v Stafford Road 06/11/1880 | View match | |
| St Peters Institute v Hendon FC 06/11/1880 | View match | |
| Swifts v Old Foresters 06/11/1880 | View match | |
| West End v Hanover United 06/11/1880 | View match | |
| Birmingham Calthorpe v Grantham Town 11/11/1880 | View match | |
| Acton v Kildare 13/11/1880 | View match | |
| Clapham Rovers v Finchley 13/11/1880 | View match | |
| Darwen v Brigg Town 13/11/1880 | View match |