| Wycombe Wanderers FC v Burton Albion FC 09/11/2021 | £5.00 | |
| Burton Albion FC v Charlton Athletic FC 13/11/2021 | £7.50 | |
| Sheffield Wednesday FC v Gillingham FC 13/11/2021 | £7.50 | |
| Rochdale FC v Leyton Orient FC 13/11/2021 | £7.50 | |
| Tranmere Rovers FC v Sutton United 13/11/2021 | £7.50 | |
| Barrow AFC v Crawley Town FC 20/11/2021 | £8.50 | |
| Newport County AFC v Swindon Town FC 20/11/2021 | £7.50 | |
| Huddersfield Town FC v West Bromwich Albion FC 20/11/2021 | £7.50 | |
| Swansea City FC v Blackpool FC 20/11/2021 | £8.50 | |
| Doncaster Rovers FC v Lincoln City FC 20/11/2021 | £6.99 | |
| Aston Villa FC v Brighton & Hove Albion FC 20/11/2021 | £7.50 | |
| Aston Villa FC v Brighton & Hove Albion FC 20/11/2021 | £6.00 |