| Chelsea FC v Malmo FF 20/10/2021 | £7.50 | |
| Huddersfield Town FC v Birmingham City FC 20/10/2021 | £7.50 | |
| Swansea City FC v West Bromwich Albion FC 20/10/2021 | £8.50 | |
| West Ham United FC v Racing Genk 21/10/2021 | £7.50 | |
| Arsenal FC v Aston Villa FC 22/10/2021 | £7.50 | |
| Brighton & Hove Albion FC v Manchester City FC 23/10/2021 | £7.50 | |
| Crystal Palace FC v Newcastle United FC 23/10/2021 | £7.50 | |
| Leeds United FC v Wolverhampton Wanderers FC 23/10/2021 | £7.50 | |
| Southampton FC v Burnley FC 23/10/2021 | £7.50 | |
| AFC Wimbledon FC v Wigan Athletic FC 23/10/2021 | £7.50 | |
| Burton Albion FC v Oxford United FC 23/10/2021 | £7.50 | |
| Doncaster Rovers FC v Cheltenham Town FC 23/10/2021 | £6.99 |