| Gillingham FC v Wigan Athletic FC 02/10/2021 | £7.50 | |
| Lincoln City FC v Plymouth Argyle FC 02/10/2021 | £7.50 | |
| Sheffield Wednesday FC v Oxford United FC 02/10/2021 | £8.50 | |
| Brighton & Hove Albion FC v Arsenal FC 02/10/2021 | £7.50 | |
| Chelsea FC v Southampton FC 02/10/2021 | £5.99 | |
| Leeds United FC v Watford FC 02/10/2021 | £7.50 | |
| Manchester United FC v Everton FC 02/10/2021 | £5.99 | |
| Liverpool FC v Manchester City FC 03/10/2021 | £14.50 | |
| Crystal Palace FC v Leicester City FC 03/10/2021 | £7.50 | |
| Tranmere Rovers FC v Colchester United FC 08/10/2021 | £7.50 | |
| Barrow AFC v Leyton Orient FC 09/10/2021 | £8.50 | |
| Newport County AFC v Bradford City FC 09/10/2021 | £7.50 |