| Morecambe FC v Plymouth Argyle FC 23/10/2021 | £7.50 | |
| Sheffield Wednesday FC v Lincoln City FC 23/10/2021 | £8.50 | |
| AFC Bournemouth v Huddersfield Town FC 23/10/2021 | £6.99 | |
| Cardiff City FC v Middlesbrough FC 23/10/2021 | £8.00 | |
| Luton Town FC v Hull City FC 23/10/2021 | £9.00 | |
| Peterborough United FC v Queens Park Rangers FC 23/10/2021 | £7.50 | |
| Rochdale FC v Sutton United 23/10/2021 | £7.50 | |
| Tranmere Rovers FC v Northampton Town FC 23/10/2021 | £7.50 | |
| Brentford FC v Leicester City FC 24/10/2021 | £7.50 | |
| Doncaster Rovers FC v Cambridge United FC 26/10/2021 | £6.99 | |
| Arsenal FC v Leeds United FC 26/10/2021 | £7.50 | |
| Chelsea FC v Southampton FC 26/10/2021 | £7.50 |