| AFC Bournemouth v Southampton FC 01/03/2016 | £6.00 | |
| Southampton FC v Liverpool FC 20/03/2016 | £5.50 | |
| Southampton FC v Manchester City FC 01/05/2016 | £6.00 | |
| Southampton FC v Manchester City FC 01/05/2016 | £4.00 | |
| Tottenham Hotspur FC v Southampton FC 08/05/2016 | £6.00 | |
| Tottenham Hotspur FC v Southampton FC 08/05/2016 | £6.50 | |
| Arsenal FC v Southampton FC 10/09/2016 | £6.50 | |
| Southampton FC v Chelsea FC 30/10/2016 | £17.00 | |
| Southampton FC v Internazionale/Inter Milan 03/11/2016 | £2.50 | |
| Southampton FC v Liverpool FC 19/11/2016 | £6.50 | |
| Southampton FC v Everton FC 27/11/2016 | £6.50 | |
| Arsenal FC v Southampton FC 30/11/2016 | £7.50 |