| Arsenal FC v Southampton FC 02/12/2000 | £1.50 | |
| Southampton FC v Leeds United FC 09/12/2000 | £5.00 | |
| Ipswich Town FC v Southampton FC 16/12/2000 | £5.00 | |
| Southampton FC v Tottenham Hotspur FC 27/12/2000 | £4.50 | |
| Southampton FC v Tottenham Hotspur FC 27/12/2000 | £5.50 | |
| Southampton FC v Tottenham Hotspur FC 27/12/2000 | £4.00 | |
| Southampton FC v Derby County FC 30/12/2000 | £5.50 | |
| Southampton FC v Derby County FC 30/12/2000 | £4.50 | |
| Southampton FC v Derby County FC 30/12/2000 | £2.50 | |
| Southampton FC v Sheffield United FC 06/01/2001 | £5.50 | |
| Southampton FC v Charlton Athletic FC 13/01/2001 | £4.00 | |
| Tottenham Hotspur FC v Southampton FC 20/01/2001 | £3.00 |