| Leicester City FC v Southampton FC 22/05/2022 | £7.50 | |
| Tottenham Hotspur FC v Southampton FC 06/08/2022 | £8.00 | |
| Tottenham Hotspur FC v Southampton FC 06/08/2022 | £7.00 | |
| Southampton FC v Leeds United FC 13/08/2022 | £8.00 | |
| Cambridge United FC v Southampton FC 23/08/2022 | £8.00 | |
| Southampton FC v Manchester United FC 27/08/2022 | £8.00 | |
| Southampton FC v Arsenal FC 23/10/2022 | £8.00 | |
| Southampton FC v Lincoln City FC 20/12/2022 | £8.00 | |
| Southampton FC v Manchester City FC 11/01/2023 | £8.00 | |
| Southampton FC v Newcastle United FC 24/01/2023 | £8.00 | |
| Newcastle United FC v Southampton FC 31/01/2023 | £9.99 | |
| Southampton FC v Grimsby Town FC 01/03/2023 | £8.00 |