| Old Foresters v Morton Rangers 05/11/1881 | View match | |
| Old Harrovians v Olympic XI 05/11/1881 | View match | |
| Reading FC v Hendon FC 05/11/1881 | View match | |
| Royal Engineers v Kildare 05/11/1881 | View match | |
| Sheffield F.C v Brigg Britannia 05/11/1881 | View match | |
| The Wednesday v Sheffield Providence 05/11/1881 | View match | |
| Small Heath v Derbyshire FC 05/11/1881 | View match | |
| Staveley v Spilsby 05/11/1881 | View match | |
| Swifts v Herts Rangers 05/11/1881 | View match | |
| Wednesbury Old Athletic v Birmingham St Georges 05/11/1881 | View match | |
| Wednesbury Strollers v Stafford Road 05/11/1881 | View match | |
| West End v Remnants 05/11/1881 | View match |